OEM Miniature Cooling Modules for Scalp Cooling Systems
Embedded Cooling Systems for Active Scalp Cooling Devices
Aspen Systems designs and manufactures OEM-grade miniature cooling modules that serve as the internal thermal engine inside active scalp cooling machines. Aspen does not manufacture or sell scalp cooling devices or cold caps to patients. Instead, we partner with medical device OEMs to deliver compact, high-performance cooling systems engineered for seamless integration into scalp cooling platforms.
Our miniature chillers provide precise, continuous temperature control, high cooling density, and medical-grade reliability—enabling OEMs to develop portable, quiet, and clinically effective scalp cooling equipment.
Aspen’s cooling modules are embedded inside customers’ medical devices to regulate coolant temperature delivered to external scalp interfaces designed and supplied by the device manufacturer.
Our miniature vapor-compression systems provide up to 1400 W of stable, continuous cooling in compact form factors optimized for integration into scalp cooling platforms.
Why Active Scalp Cooling Matters
Active scalp cooling relies on precise, consistent temperature control to reduce chemotherapy-induced alopecia. By lowering scalp temperature, blood flow and metabolic activity at the hair follicles are reduced, limiting drug exposure to rapidly dividing cells.
Challenges with legacy approaches
- Frozen gel caps: Inconsistent temperature, frequent swaps, and increased staff burden
- Large console units: Restrict patient mobility and valuable clinic space
- Poor temperature stability: Temperature drift can compromise alopecia prevention outcomes
What clinics & OEMs need and Aspen Systems Delivers
- Compact, low-noise modules delivering high cooling density
- Precise, continuous temperature control across pre-cool, infusion, and post-cool phases
- Easy system integration, low maintenance, and medical-grade reliability
Miniature Cooling Modules for Cold Cap Systems
Aspen Systems miniature chillers are designed to be integrated into cold cap and scalp cooling systems developed by medical device OEMs. Modules are available as drop-in solutions or custom-configured assemblies. Contact us for datasheets, thermal specifications, and integration guidance.
Key Features & Advantages
- High cooling density in small form factors — industry-leading watts-per-volume
- Precision temperature control — supports stable scalp temperatures throughout the full therapy cycle
- Modular, scalable architecture — adaptable across multiple cold cap designs and flow paths
- Low noise and clinical reliability — engineered for use in medical environments
| Chiller Model | Cooling Capacity | Dimensions | Weight |
|---|---|---|---|
| LCM-600 | 600 Watts | 134H x 199W x 161D mm (5.3H x 7.8W x 6.3D in) |
2.7 kg (6.0 lbs) |
| LCM-600G natural refrigerant |
600 Watts | 134H x 199W x 161D mm (5.3H x 7.8W x 6.3D in) |
2.7 kg (6.0 lbs) |
| LCM-650 | 650 Watts | 137H x 192W x 225D mm (5.4H x 7.6W x 8.9D in) |
2.9 kg (6.3 lbs) |
| LCM-650G natural refrigerant |
650 Watts | 137H x 192W x 225D mm (5.4H x 7.6W x 8.9D in) |
2.9 kg (6.3 lbs) |
| LCM-900 | 900 Watts | 137H X 192W X 224D mm (5.4H X 7.6W X 8.8D in) |
3 kg (6.6 lbs) |
| LCM-900G natural refrigerant |
900 Watts | 137H X 192W X 224D mm (5.4H X 7.6W X 8.8D in) |
3 kg (6.6 lbs) |
| LCM-1400 | 1400 Watts | 212H X 337W X 228D mm (8.3H X 13.3W X 9D in) |
5.5 kg (12 lbs) |
| LCM-1400G natural refrigerant |
1400 Watts | 212H X 337W X 228D mm (8.3H X 13.3W X 9D in) |
5.5 kg (12 lbs) |
Integration & Engineering Support
Aspen Systems partners with medical device OEMs and system integrators to reduce thermal risk and accelerate development of scalp cooling platforms. Our engineering team supports the integration of miniature vapor-compression cooling modules into existing device architectures, helping ensure reliable performance, predictable thermal behavior, and a smoother path from prototype to production.
- Thermal modeling, CFD analysis, and prototyping
- Custom mechanical packaging and tubing interfaces
- Control firmware and API integration
- Regulatory and verification support, including EMC, safety, and life-cycle testing
Internal cooling engine designed by Aspen Systems
Customer Success — Enabling Proven Cold Cap Systems
Aspen Systems miniature chillers are trusted by medical device manufacturers as the cooling subsystem within clinically deployed scalp cooling solutions.
“Our original systems were based on re-freezable gel packs. We realized early on that active cooling would be needed for chemo procedures. Aspen supplied the Liquid Chiller Module LCM-900 that demonstrated excellent temperature stability in a small, lightweight package. Knowing we were getting technology that was military-hardened gave us the confidence that the reliability would match our clinical application.” — Christopher Blodgett, President, Welkins LLC
“The small, lightweight TRS-2 benefits both the patient and the clinic. For cold cap therapy, the patient can easily use scalp cooling before, during, and after chemo treatment. Portability allows the practitioner to free up the infusion chair immediately after treatment.” — Ciro D’Angelo, CEO, Arctic Cold Caps
Customer Success — How Aspen Systems Cooling Enables the Cooler Heads Scalp Cooling Platform
Aspen Systems supplies the miniature liquid chiller modules that power Cooler Heads’ portable scalp cooling system. By integrating Aspen’s compact, high-performance cooling technology into their device architecture, Cooler Heads delivers consistent, controlled scalp hypothermia throughout chemotherapy treatment.
Why this matters
- Supports portability: Aspen’s compact cooling modules enable mobile scalp cooling without bulky consoles or dry ice
- Delivers reliable thermal performance: Stable cooling in a lightweight (<7 lb) module designed for continuous operation
- Improves system efficiency: Vapor-compression cooling outperforms thermoelectric alternatives in power consumption and temperature stability
- Accelerates development: Aspen’s engineering support helped Cooler Heads iterate quickly and deploy a dependable solution
“We have been very pleased with Aspen Systems’ products and service — a 10/10 partnership which has allowed us to carry out our mission to save lives.” — Kate Dilligan, CEO & Founder, Cooler Heads
Frequently asked questions
How cold do scalp cooling systems need to get to reduce hair loss?
Most clinical protocols target scalp temperatures between 0°C and 5°C during chemotherapy infusion. Maintaining consistent temperature control throughout treatment is critical.
What cooling technology is best for cold cap systems?
Active refrigeration using miniature vapor-compression systems provides more consistent and repeatable cooling than passive ice or gel-based approaches.
Can Aspen Systems cooling modules be integrated into different cold cap designs?
Yes. Aspen works with OEMs to tailor flow rates, tubing interfaces, and control strategies to match each system’s architecture.
Are Aspen Systems cooling modules compliant with medical safety standards?
Aspen Systems’ modules are designed to support medical device integration, and our team assists OEMs with EMC testing, safety validation, and development processes aligned with FDA and ISO 13485 requirements.
Get a Quote | Application Questions
Please send us your requests; our team is happy to help.
You can also reach us by email at: info@aspensystems.com
or by phone number at (508) 281-5322